Strategic Brief · Privileged & Confidential
Ahead of the LS&H carve-out close  ·  Confidential  ·  Prepared for Altaris

The growth layer for LS&H. Already built.

You are standing up Clarivate’s Life Sciences & Healthcare business — Cortellis and DRG — as an independent platform. Cortellis answers the molecule’s R&D questions. DRG answers its commercialization questions. HealthTech Alpha answers what your customers ask next: what the healthcare innovation ecosystem is doing around the molecule. This is not a better Cortellis. It is the layer Cortellis was never built to be — eleven years in the making, by Galen Growth.

~2,500LS&H accounts incl. the top-20 pharma — the channel the module ships into
17,000+healthcare-innovation companies Galen tracks, across 100+ countries
>1.5Bstructured & unstructured data points, evidence-graded and scored
See It In Action

From strategic question to board-ready recommendation — live.

Rather than describe HealthTech Alpha, we built a live, interactive demonstration of the decision workflow at its heart — so the Altaris team can put its hands on it before we ever get to a data room.

Franchise Lifecycle Intelligence — a working decision workflow, on real HealthTech Alpha data.

Choose a therapeutic area, a business objective, a region and a planning horizon — defending a franchise facing LOE, say, or mapping five years of obesity innovation — and watch the platform convert that question into an innovation landscape, priority opportunities, competitor intelligence, scenario analysis and an executive recommendation.

ScanShortlistCompareEvaluateMonitor

It is the fastest way to understand what LS&H’s ~2,500 accounts would be getting: not another database, but a decision engine — the enterprise workflow logic Cortellis and DRG customers already run, applied to the innovation ecosystem around the molecule.

Open the live demonstration →

decision-workflow.galengrowth.com · every figure drawn from actual HealthTech Alpha data · variable set, weighting and scoring logic deliberately simplified for illustration

And when you are ready, the Galen Growth principals will run the combined graph live on one therapeutic area — HealthTech Alpha entities crosswalked to Cortellis pipeline and DRG market-access views, on your accounts’ own questions. Which digital-therapeutics products in type-2 diabetes have peer-reviewed adherence evidence — and which top-20 pharma do they partner with? Which CGM-adjacent ventures hold FDA clearance plus an active pharma co-development? Which technologies will shape market access for the next GLP-1 generation? The gap is the thesis — shown on a single screen.

The Strategic Moment

The day-one roadmap is being written now.

Altaris is carving Clarivate’s Life Sciences & Healthcare business out for $600M — roughly 1.5× 2025 revenue on a ~$390M business — to run as an independent life-sciences intelligence platform, with close expected H2 2026. The roadmap you write between signing and close decides what that platform is on day one: a separation story, or a growth story. This page is about one decision on that roadmap.

The market priced LS&H the way it prices any scaled asset without a growth story. You bought the platform; what re-rates it is growth and workflow ownership. HealthTech Alpha is the growth layer that arrives complete — a new sellable coverage module, an entity-resolved crosswalk into Cortellis and DRG, and the evidence-graded data foundation the platform’s AI roadmap requires.

Cortellis and DRG own the molecule’s lifecycle. HealthTech Alpha owns the innovation ecosystem around it.

That is the read-across in one line: adjacency, not overlap. LS&H owns R&D, regulatory, epidemiology and market-access intelligence for the molecule; HealthTech Alpha extends the same intelligence stack into the 17,000+ ventures and products that pharma, medtech, payers, investors and providers now track as seriously as pipelines — and sells it to the same enterprise seats.

The Gap

Complementary, not competitive — and categorically different.

Galen Growth is the company behind HealthTech Alpha: a specialist intelligence platform for healthcare technology innovation. It is not a database to be re-keyed. It is the evidence-graded layer for the part of life sciences the LS&H platform doesn’t see — already structured, already scored, already in production with the same top-20 pharma on your platform.

Cortellis + DRG cover
Drug R&D and development intelligence
Regulatory, safety and pharmacovigilance
Epidemiology and forecasting
Payer insights, market access, commercialization
HealthTech Alpha adds
Healthcare-technology ventures, products & platforms — with partnerships, trials, regulatory status and patents
Evidence grading: peer-reviewed clinical evidence distinguished from marketing claims
Maturity scoring, ecosystem mapping, decision workflows
In production today with the same top-20 pharma on your platform

The differentiation is not raw data — it is what the data becomes.

Much of the underlying source material is public; that is precisely the point. HealthTech Alpha’s value is how it collects, structures, normalises and indexes fragmented healthcare-innovation information into decision-grade intelligence: a healthcare-native ontology rather than keyword search; a venture-product-evidence graph connecting companies to products, trials, approvals, customers and partnerships; longitudinal global coverage; and proprietary signals — Alpha Score, Evidence Signal, Partnership Signal, Team Signal, Product Score — that raw access to the same sources cannot reproduce.

Zero overlap. Antitrust-trivial. And the trust layer under the AI roadmap.

Nothing in the module competes with a Cortellis or DRG product line, so the addition is clean to execute even inside a carve-out. And as AI becomes the interface, generic answers are not enough — the data layer itself has to be curated, indexed and auditable, which is exactly what a raw LLM cannot provide. Evidence grading and codified expert judgement are precisely that infrastructure: a workflow and a customer base built over eleven years, not a feature to ship.

The Questions

The five questions that decide strategic fit. Answered directly.

Every serious acquirer of this asset asks the same five questions. Here are the answers, plainly.

1

How do clients solve this today?

With a patchwork: generalist databases that are funding-first and weak on healthcare evidence and product depth; Google and manual research that is slow and hard to reproduce; internal spreadsheets that fragment and date quickly; consultants who are point-in-time; expert networks that don’t scale — and, increasingly, general-purpose LLMs that are plausible but ungrounded, with no provenance and no audit trail.

2

What triggers adoption of HealthTech Alpha?

The moment a team must move from a broad market question to something defensible: a shortlist, a competitor map, a portfolio view, a partner universe, a board-ready decision. That is where the patchwork breaks and HTA becomes compelling.

3

What is unique about the data and intelligence?

Not raw access — conversion. The healthcare-native ontology, the venture-product-evidence graph, the longitudinal coverage and the proprietary scoring turn public fragments into decision-grade intelligence. The live demonstration shows the result in practice.

4

What traction has HTA seen?

Adopted across pharma, medtech, health insurers, health systems, investors and advisors — large pharma, medical-device firms, insurers, public-health bodies and consultancies among them — on repeatable use cases: ecosystem mapping, competitor benchmarking, partner scouting, portfolio evaluation and market intelligence. The product has evolved from database to intelligence platform: Alpha Copilot, Alpha Edge, scoring, signals and enterprise access. Shown here at a strategic level; diligence detail follows the fit discussion.

5

Where does LS&H accelerate this?

Adjacency, not overlap. LS&H owns the molecule’s lifecycle intelligence; HTA extends the same stack into the innovation around it — digital health, AI-enabled care models, clinical-trial innovation, patient support, evidence generation, and partnership and commercialisation pathways — shipped as a module through the commercial engine you already run, into ~2,500 accounts, plus buyer types the platform doesn’t yet serve at scale: investors, payers, providers, consultancies.

Don’t take the answers on faith

The fastest check on all five is the live decision-workflow demonstration — a strategic question in, an evidence-based recommendation out, on actual HealthTech Alpha data. Open the demo →

The Integration

Trained in — not bolted on.

Put the engine inside the platform you just bought — don’t bolt a layer onto the side of it.

A

An entity-resolved crosswalk

HealthTech Alpha’s ontology joins its companies, products, partnerships, trials and regulatory records to Cortellis pipeline entities and DRG market-access data — one resolved graph from molecule to innovation ecosystem.

B

A new module in the existing motion

Healthcare-technology innovation intelligence ships as a module in the commercial engine you already run — an upsell to ~2,500 accounts, plus buyer types the platform doesn’t yet serve at scale: investors, payers, providers, consultancies.

C

The trust layer under the AI roadmap

AI-enabled intelligence workflows need curated, auditable domain data. Evidence grading is precisely that infrastructure — a workflow and a customer base built over eleven years, not a feature to ship.

D

The decision workflow travels with it

HTA supports the decision workflow around the molecule: where to partner, where to acquire, where to monitor, and where competitors are already moving — scan → shortlist → compare → evaluate → monitor, as the demonstration shows live.

The Owner’s Math

Run your own assumptions.

Illustrative, deliberately conservative, and yours to replace. Three levers decide what the module is worth to the platform.

Attach rate — of ~2,500 accounts 5%
Module price — per account / yr $40K
Exit multiple — of revenue 2.0×
$5.0M
module ARR, growing from day one
+1.3pts
on platform organic growth (2025 base −1.4%) — the sign flips
+$195M
enterprise value vs. the ~1.5× entry, on ~$390M revenue
Every 0.1× of exit-multiple improvement ≈ $39M of enterprise value. The module’s ARR pays for the workstream; the multiple pays for the deal.
The Clock

Why now.

A build cannot close this gap on a carve-out timeline — and the window to shape the day-one roadmap is between signing and close.

The build alternative: 5–7 years, $50M–$75M
Per Galen Growth’s published Value Defender analysis — across proprietary data, evidence-linked ontology, expert validation and global commercial trust — with execution risk, not cost, as the central concern. The principals are flexible on structure and terms.
A growth story at close
Every carve-out launches with a separation story. A signed growth module, timed to close, lets the platform launch with a growth story instead — to customers, to talent, and eventually to the exit market.
Your own playbook
Simulations Plus combining with Chemical Computing Group is Altaris assembling a platform on the biosimulation leg. HealthTech Alpha into LS&H is the same move on the intelligence leg.
The commercial engine is the upside
The asset is more mature than its commercial engine — and that gap is the value-creation opportunity. With LS&H’s enterprise packaging, commercial structure and ~2,500 life-sciences accounts, HTA revenue can accelerate well beyond what Galen would reach standalone. It is exactly the kind of upside a carve-out value-creation plan exists to capture.

The keystone thesis.

“Bolted into Cortellis and DRG, HealthTech Alpha is immediately accretive — and strategically decisive: it extends the platform from the molecule lifecycle to the innovation ecosystem its customers increasingly pay to understand.”

The Trust

Why available, why you.

Galen Growth has been deliberate about where eleven years of curation lands. The right home is the platform where healthcare-technology intelligence becomes core infrastructure for the industry — not a feature inside someone else’s product. A focused, independent LS&H, resourced by a healthcare-exclusive owner, is that home. The principals seek an outright sale, are flexible on structure and timing — including alignment to your close calendar — and intend to lead the layer inside the platform.

The strategic process is being run by Kane & Company, retained sell-side advisor to Galen Growth. Principal participation is available once a mutual NDA is in place.

The Next Step

Thirty minutes, before close.

Thirty minutes where the Galen Growth principals show the combined graph on one therapeutic area — HealthTech Alpha crosswalked to Cortellis and DRG views, on your accounts’ own questions. The live decision-workflow demonstration is open now, and the full brief is available on request.

Advisor & Contact
Michael Kane, Ph.D., J.D.
Managing Partner, Kane & Company
FINRA / SEC / SIPC–Registered Investment Bank
34 years of M&A and investment-banking experience

Commerce@kaneco.com  ·  310-441-5263
Representing
Galen Growth
Developer of HealthTech Alpha — specialist healthcare innovation intelligence
One platform. One trusted source.
Request the demonstration → Open the live demonstration Call 310-441-5263